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Canine Parvovirus VP2 Monoclonal Antibody (4G2)
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产品信息
MA571820
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
4G2
抗原
Recombinant Canine parvovirus Capsid protein VP2.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Canine parvovirus (CPV) is a highly contagious virus affecting dogs, with VP2 being one of the key structural proteins of the virus. The VP2 protein is the major capsid protein and plays a crucial role in the virus's ability to infect host cells and elicit an immune response. VP2 makes up approximately 90% of the viral capsid and is involved in host cell receptor binding, viral entry, and the assembly of new virions.Structurally, VP2 assembles into an icosahedral capsid, providing stability and protection to the viral genome. The protein is known for its antigenic variability, which allows the virus to evade the host's immune system. Mutations in the VP2 gene are responsible for the emergence of new CPV strains with different host ranges and pathogenicities.Functionally, the VP2 protein is a major target for neutralizing antibodies. Vaccines against CPV often include the VP2 protein to induce immunity. The immune response to VP2 is critical for the protection of dogs against parvovirus infection, making it an important protein in both the pathogenicity of the virus and the development of effective vaccines.
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