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Nordic
Carboxypeptidase A Polyclonal Antibody, Biotin
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产品信息
NE025-BIO
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carboxypeptidase A from Bovine pancreas
偶联物
形式
Lyophilized
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Carboxypeptidase A isolated and purified from bovine pancreas. Freund's complete adjuvant is used in the first step of the immunization procedure.
No preservative added, as it may interfere with the antibody activity. No foreign protein added. It is reconstituted by adding 1.0 mL sterile distilled water, spun down to remove insoluble particles, divided into small aliquots, frozen and stored at or below -20°C.
靶标信息
CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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