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Proteintech
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Immunogen sequence: FLAQYLCNE YQKGNETIVN LIHSTRIHIM PSLNPDGFEK AASQPGELKD WFVGRSNAQG IDLNRNFPDL DRIVYVNEKE GGPNNHLLKN MKKIVDQNTK LAPETKAVIH WIMDIPFVLS ANLHGGDLVA NYPYDETRSG SAHEYSSSPD DAIFQSLARA YSSFNPAMSD PNRPPCRKND DDSSFVDGTT NGGAWYSVPG GMQDFNYLSS NCFEITVELS CEKFPPEETL KTYWEDNKNS LISYLEQIHR GVKGFVRDLQ GNPIANATIS VEGIDHDVTS AKDGDYWRLL IPGNYKLTAS APGYLAITKK VAVPYSPAAG VDFELESFSE RKEEEKEELM EWWKMMSETL NF (126-476 aa encoded by BC033866)
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Carboxypeptidase E; Carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Enkephalin convertase; insulin granule-associated carboxypeptidase; Prohormone-processing carboxypeptidase
基因别名: CARBE; CPE; CPH; Cph-1; Cph1; fat; R74677
UniProt ID: (Human) P16870, (Rat) P15087, (Mouse) Q00493
Entrez Gene ID: (Human) 1363, (Rat) 25669, (Mouse) 12876