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Invitrogen
Cardiac Troponin T Monoclonal Antibody (3D6)
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产品信息
MA1-24616
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3D6
抗原
Full length human protein.
偶联物
形式
Liquid
保存条件
4°C, do not freeze
运输条件
Wet ice
产品详细信息
MA1-24616 detects cardiac Troponin T from human, mouse, bovine, canine, fish, goat, and rabbit samples. MA1-24616 will not react with rat, feline, or porcine.
MA1-24616 has been successfully used in ELISA and Western blot procedures.
The MA1-24616 immunogen is full length human protein.
靶标信息
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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