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Invitrogen
Caspase 13 Polyclonal Antibody
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产品信息
PA5-19949
产品规格
种属反应
Bovine,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide near the amino terminus of bovine Caspase-13
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Ion-exchange chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In Western blot applications, this antibody detects a band at ~43kDa.
A suggested positive control is HL60 cell lysate.
PA5-19949 can be used with blocking peptide PEP-0074.
The immunogen is located within amino acids 80 - 130 of Caspase-13.
靶标信息
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis-related cysteine protease; CASP-13; CASP-4; CASP13; caspase 4, apoptosis-related cysteine protease; Caspase-13; Caspase-4; ERICE; Evolutionary related interleukin-1-beta-converting enzyme; MGC137679
基因别名: CASP13; CASP4
UniProt ID: (Bovine) Q5E9C1
Entrez Gene ID: (Bovine) 338039
