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Caspase-3 p17 subunit Polyclonal Antibody, Alexa Fluor™ 647
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产品信息
BS-20363R-A647
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit (amino acids 21-120).
偶联物
Alexa Fluor™ 647
Alexa Fluor™ 647
Alexa Fluor™ 647
激发/发射光谱
650/671 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
规格
100 µg
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
CASP3 (Caspase3 Apoptosis-Related Cysteine Protease), also known as YAMA, CPP32 or APOPAIN, is a caspase protein that interacts with caspase 8 and caspase 9. It is encoded by the CASP3 gene. The CASP3 protein is a member of the cysteine-aspartic acid protease (caspase) family. Tiso et al. (1996) used radiation hybrid mapping to localize the CPP32 gene to human chromosome 4q33-q35.1. Fernandes-Alnemri et al. (1994) found that overexpression of CPP32 in insect cells induced apoptosis. Coexpression of the 2 CPP32 subunits in insect cells also resulted in apoptosis. Tewari et al. (1995) showed that purified human ICE cleaved the Yama proenzyme into a proteolytically active form and that activated Yama cleaved PARP into the 85-kD apoptotic form.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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