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Invitrogen
Caspase 4 Polyclonal Antibody
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Caspase 4 Antibody (PA5-29788) in IHC (P)
Caspase 4 Polyclonal Antibody detects CASP4 protein at cytosol on SAS xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SAS xenograft. Caspase 4 Polyclonal Antibody (Product # PA5-29788) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-29788
产品规格
种属反应
Dog,
Human,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Caspase 4. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.89 mg/mL
规格
89 µg
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: H1299, K562, THP-1, HL-60, myc-tagged human caspas4-transfected 293T cells.
Predicted reactivity: Rhesus Monkey (96%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CASP-1; CASP-4; Caspase-1; caspase-1/caspase-4 hybrid; Caspase-4; ICE; ICE and Ced-3 homolog 2; ICE(rel)-II; ICH-2; IL-1 beta-converting enzyme; IL-1BC; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; member of caspase family; Mih1; p45; Protease TX
基因别名: CASP1; CASP4; ICH2; IL1BC
UniProt ID: (Dog) Q9MZV7
Entrez Gene ID: (Dog) 403724
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
