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Proteintech
Caspase 9/p35/p10 Polyclonal Antibody, CoraLite® Plus 488
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Caspase 9/p35/p10 Antibody (CL48810380100UL) in Flow
1X10^6 HepG2 cells were intracellularly stained with 0.4 µg CoraLite 488 Anti-Human Caspase 9/p35/p10 (Product # CL48810380100UL)) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CL48810380100UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
靶标信息
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 25 kDa caspase-9 dominant negative protein; apoptotic protease activating factor 3; apoptotic protease MCH-6; apoptotic protease-activating factor 3; carboxy-terminal divergent isoform; CASP9; caspase 9, apoptosis-related cysteine peptidase; caspase 9b; caspase-9 dominant negative form; caspase-9 variant; caspase-9-carboxyl-terminal divergent; ICE-like apoptotic protease 6; protein phosphatase 1, regulatory subunit 56; unnamed protein product
基因别名: APAF-3; APAF3; CASP-9; Casp-9-CTD; Casp9_v1; Caspase-9; ICE-LAP6; MCH6; PPP1R56
UniProt ID: (Human) P55211, (Mouse) Q8C3Q9
Entrez Gene ID: (Human) 842, (Mouse) 12371, (Rat) 58918
response to hypoxia
kidney development
response to ischemia
proteolysis
apoptotic process
cellular response to DNA damage stimulus
intrinsic apoptotic signaling pathway in response to DNA damage
response to UV
protein processing
response to cobalt ion
response to estradiol
response to lipopolysaccharide
glial cell apoptotic process
cellular response to UV
signal transduction in response to DNA damage
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
response to ethanol
protein maturation
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to dexamethasone stimulus
response to indole-3-methanol
leukocyte apoptotic process
response to anesthetic
intrinsic apoptotic signaling pathway
positive regulation of execution phase of apoptosis
response to auditory stimulus
animal organ development
system development
platelet formation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
