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Invitrogen
Cathepsin 1/7 Monoclonal Antibody (228905)
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产品信息
MA5-60991
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
228905
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Cathepsin 7/Cathepsin 1, Ala18-Leu331
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Cathepsins are a family of proteases, and Cathepsins B and L (sometimes referred to as Cathepsin 1 and Cathepsin 7, respectively) are notable members of this group. These enzymes are primarily involved in the degradation of proteins within lysosomes, contributing to cellular turnover and homeostasis. Cathepsin B, encoded by the CTSB gene, is a cysteine protease that participates in various physiological processes, including protein catabolism, antigen processing, and apoptosis. Similarly, Cathepsin L, encoded by the CTSL gene, also functions as a cysteine protease and is crucial for normal cellular functions, such as tissue remodeling and immune responses. Dysregulation of these enzymes has been implicated in numerous pathological conditions, including cancer, neurodegenerative diseases, and inflammatory disorders. Understanding the roles and regulation of Cathepsin B and Cathepsin L can provide valuable insights into disease mechanisms and potential therapeutic interventions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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