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Invitrogen
Cbl-b Polyclonal Antibody
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Cbl-b Antibody (PA5-102547) in IHC (P)
Immunohistochemistry analysis of Cbl-b in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Cbl-b polyclonal antibody (Product # PA5-102547) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102547
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CBLB(Accession Q13191), corresponding to amino acid residues M1-V33.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CBLB.
靶标信息
This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the nucleus in testis and several other cell types.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cas-Br-M (murine) ecotropic retroviral transforming sequence b; Cas-Br-M (murine) ectropic retroviral transforming sequence b; Casitas B-lineage lymphoma b; Casitas B-lineage lymphoma proto-oncogene b; Cbl proto-oncogene, E3 ubiquitin protein ligase B; E3 ubiquitin-protein ligase CBL-B; RING finger protein 56; RING-type E3 ubiquitin transferase CBL-B; SH3-binding protein CBL-B; Signal transduction protein CBL-B
基因别名: AI429560; AI851073; Cbl-b; CBLB; Nbla00127; RNF56
UniProt ID: (Rat) Q8K4S7, (Mouse) Q3TTA7
Entrez Gene ID: (Rat) 171136, (Mouse) 208650
phosphotyrosine binding
ubiquitin-protein transferase activity
signal transducer activity
calcium ion binding
zinc ion binding
ligase activity
protein kinase binding
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
damaged DNA-binding protein
ligase
metabolite interconversion enzyme
positive regulation of T cell anergy
immune response
signal transduction
cell surface receptor signaling pathway
response to gravity
response to hormone
protein ubiquitination
regulation of signaling
intracellular signal transduction
T cell activation
positive regulation of protein catabolic process
negative regulation of alpha-beta T cell proliferation
negative regulation of T cell receptor signaling pathway
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