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Proteintech
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Immunogen sequence: ANQRCSSPKG SARNSLVKAK RKGSVSVCSK ESPSSSSESE SCDESISDGP SKVTLEARNS SEKLPTELSK EEPSTKNTTA DKLAIKLGFS LTPSKGKTSG TTSSSSDSSA ESDDQCLMSS STPECAAGFL KTVGLFAGRG RPGPGLSSQT AGAAGWRRSG SNGGGQAPGA SPSVSLPASL GRGWGREENL FSWKGAKGRG MRGRGRGRGH PVSCVVNRST DNQRQQQLND VVKNSSTIIQ NPVETPKKDY SLLPLLAAAP QVGEKIAFKL LELTSSYSPD VSDYKEGRIL SHNPETQQVD IEILSSLPAL REPGKFDLVY HNENGAEVVE YAVTQESKIT VFWKELIDPR LIIESPSNTS STEPA
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coilin; coilin p80; p80; p80-coilin; unnamed protein product
基因别名: CLN80; COIL; p80-coilin
UniProt ID: (Human) P38432
Entrez Gene ID: (Human) 8161