Nordic

Complement Polyclonal Antibody

Name: Complement Polyclonal Antibody
Brand: Nordic
SKU: RAHU-C

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

RAHU-C

应用

建议稀释比

已发表文章

免疫电泳 (IE)

120 µL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Human complement

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.

Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Crossreactivity of this antiSerum has not been tested in detail.

In immunoelectrophoresis use 2 µL human plasma or equivalent against 120 µL antiserum. In double radial immunodiffusion use a rosette arrangement with 10 µL antiserum in 3 mm diameter center well and 2 µL plasma samples (neat and serially diluted) in 2 mm diameter peripheral wells. In single radial immunodiffusion use 1 percent antiserum in the gel.

Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at 4°C, not refrozen, and preferably used the same day.

靶标信息

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. C3 and C4, mainly produced by the liver, are the major plasma proteins of the immune system complement pathways. Measurements of serum complement components C3 and C4 are useful in the diagnosis and monitoring of immune complex disease.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: acidic C4; Acidic complement C4; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3a anaphylatoxin; C4A anaphylatoxin; Complement C3; Complement C4-A; complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; MHC class III region complement; prepro-C3; Rodgers form of C4

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基因别名: AHUS5; ARMD9; ASP; C3; C3a; C3b; C4; C4A; C4A2; C4A3; C4A4; C4A6; C4AD; C4S; CO4; CPAMD1; CPAMD2; HEL-S-62p; RG

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UniProt ID: (Human) P01024, (Human) P0C0L4

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Entrez Gene ID: (Human) 718, (Human) 720

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功能

serine-type endopeptidase activity endopeptidase inhibitor activity receptor binding protein binding lipid binding C5L2 anaphylatoxin chemotactic receptor binding cofactor binding complement component C1q binding protease inhibitor

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