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Invitrogen
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The monoclonal antibody 9 recognizes iC3b, C3dg and C3g in plasma. The monoclonal antibody does not recognize C3 or C3b.
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3
基因别名: C3; CPAMD1
Entrez Gene ID: (Human) 718