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Complement fragment 3c Polyclonal Antibody

查看其他5个Complement C3c抗体

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Complement fragment 3c Polyclonal Antibody

产品信息

BS-6416R

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:300-1:1,000
-

免疫组化（石蜡） (IHC (P))

1:200
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:100-1:500
-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Pig, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1, amino acids 1051-1200.
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: acylation stimulating protein; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3 convertase cleavage product; C3a anaphylatoxin; complement 3; complement component 3; complement component 3d; complement component C3; complement component C3 precursor; complement component C3a; complement component C3b; complement factor 3; epididymis secretory sperm binding protein Li 62p; prepro-C3; preprocomplement component C3; unnamed protein product

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基因别名: AHUS5; ARMD9; ASP; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp

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UniProt ID: (Mouse) P01027, (Rat) P01026, (Human) P01024, (Pig) P01025

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Entrez Gene ID: (Mouse) 12266, (Rat) 24232, (Human) 718, (Pig) 397072

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功能
antigen binding endopeptidase inhibitor activity protein binding chemokine activity lipid binding C5L2 anaphylatoxin chemotactic receptor binding receptor agonist activity receptor binding protease inhibitor
参与通路
positive regulation of type IIa hypersensitivity complement activation, lectin pathway activation of membrane attack complex positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex complement receptor mediated signaling pathway proteolysis inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway opsonization response to bacterium positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling regulation of complement activation regulation of complement activation, alternative pathway leukocyte chemotaxis killing of cells of other organism oviduct epithelium development vascular smooth muscle cell differentiation B cell activation positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of developmental growth positive regulation of phagocytosis protein maturation retina development in camera-type eye positive regulation of phagocytosis, engulfment positive regulation of ERK1 and ERK2 cascade positive regulation of glomerular mesangial cell proliferation beta-amyloid clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning complement activation, GZMK pathway positive regulation of opsonization positive regulation of sensory perception of pain negative regulation of vascular smooth muscle contraction positive regulation of apoptotic cell clearance tolerance induction response to xenobiotic stimulus response to magnesium ion response to estradiol response to progesterone response to estrogen innate immune response response to glucocorticoid innervation immune response signal transduction G-protein coupled receptor signaling pathway positive regulation of immune response response to other organism fatty acid metabolic process negative regulation of endopeptidase activity
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