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Complement fragment 3c Polyclonal Antibody

View all (5) Complement C3c antibodies

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Complement fragment 3c Polyclonal Antibody

Product Details

BS-6416R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1, amino acids 1051-1200.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Complement C3; complement component 3; complement component C3; complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; HSE-MSF; prepro-C3; unnamed protein product

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Gene Aliases: AHUS5; AI255234; ARMD9; ASP; C3; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp

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UniProt ID: (Human) P01024, (Rat) P01026, (Mouse) P01027, (Pig) P01025

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Entrez Gene ID: (Human) 718, (Rat) 24232, (Mouse) 12266, (Pig) 397072

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Function(s)
antigen binding endopeptidase inhibitor activity receptor binding protein binding chemokine activity C5L2 anaphylatoxin chemotactic receptor binding receptor agonist activity lipid binding cofactor binding protease inhibitor
Process(es)
positive regulation of type IIa hypersensitivity complement activation, lectin pathway activation of membrane attack complex positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex immune system process complement receptor mediated signaling pathway lipid metabolic process fatty acid metabolic process inflammatory response immune response complement activation complement activation, alternative pathway complement activation, classical pathway signal transduction G-protein coupled receptor signaling pathway opsonization response to bacterium positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling leukocyte chemotaxis killing of cells of other organism oviduct epithelium development B cell activation innate immune response positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of phagocytosis protein maturation positive regulation of phagocytosis, engulfment beta-amyloid clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning complement activation, GZMK pathway positive regulation of apoptotic cell clearance tolerance induction chemotaxis blood coagulation negative regulation of endopeptidase activity response to magnesium ion response to estradiol response to progesterone response to estrogen positive regulation of developmental growth response to glucocorticoid positive regulation of ERK1 and ERK2 cascade
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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