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Invitrogen
Connexin 43 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-20953
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a segment of the 3rd cytoplasmic domain of rat GJA1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
100 µg
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-20953 detects GJA1 in Human, Mouse and Rat samples.
PA1-20953 has been successfully used in Immunohistochemistry (Paraffin) and Western Blot procedures.
PA1-20953 immunogen corresponds to A synthetic peptide corresponding to a segment of the 3rd cytoplasmic domain of rat GJA1..
靶标信息
Connexin 43 (Cx43), encoded by the GJA1 gene, is a widely expressed gap junction protein that plays an important role in direct cell-to-cell communication. Six Cx43 proteins assemble to form a connexon, or hemichannel, which can pair with a connexon on a neighboring cell to create a gap junction channel. These channels allow ions, metabolites, and small signaling molecules to pass between adjacent cells, helping coordinate processes such as electrical conduction, tissue development, wound healing, and cellular homeostasis. Cx43 is especially abundant in tissues such as the heart, brain, bone, and skin, and changes in its expression, localization, or function have been associated with cardiovascular disease, neurological disorders, impaired tissue repair, and cancer. Because of its broad role in intercellular signaling and disease biology, Cx43 is an important target for studying gap junction function and developing potential therapeutic strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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