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Invitrogen
Cytokeratin 10 Polyclonal Antibody
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Cytokeratin 10 Antibody (PA5-78036) in WB
Western blot analysis of Cytokeratin 10 in various whole cell extracts (30 µg). Samples were incubated with Cytokeratin 10 polyclonal antibody (Product # PA5-78036) using a dilution of 1:500 followed by HRP-conjugated anti-rabbit IgG. Separated by 10% SDS-PAGE. Competitors antibody diluted at 1:500.
产品信息
PA5-78036
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Cytokeratin 10. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.82 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: A431, HeLa, HepG2
Predicted Reactivity: Mouse (89%), Rat (92%), Dog (92%), Bovine (89%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-10; CK-17; cytokeratin 10; Cytokeratin-10; cytokeratin-17; K10; keratin 10, type I; Keratin, type I cytoskeletal 10; Keratin-10; keratin-17
基因别名: BCIE; BIE; CK10; EHK; K10; KPP; KRT10
UniProt ID: (Human) P13645
Entrez Gene ID: (Human) 3858
