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Proteintech
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Immunogen sequence: MTTSIRQFT SSSSIKGSSG LGGGSSRTSC RLSGGLGAGS CRLGSAGGLG STLGGSSYSS CYSFGSGGGY GSSFGGVDGL LAGGEKATMQ NLNDRLASYL DKVRALEEAN TELEVKIRDW YQRQAPGPAR DYSQYYRTIE ELQNKILTAT VDNANILLQI DNARLAADDF RTKFETEQAL RLSVEADING LRRVLDELTL ARADLEMQIE NLKEELAYLK KNHEEEMNAL RGQVGGEINV EMDAAPGVDL SRILNEMRDQ YEKMAEKNRK DAEDWFFSKT EELNREVATN SELVQSGKSE ISELRRTMQA LEIELQSQLS MKASLEGNLA ETENRYCVQL SQIQGLIGSV EEQLAQLRCE MEQQNQEYKI LLDVKTRLEQ EIATYRRLLE GEDAHLTQYK KEPVTTRQVR TIVEEVQDGK VISSREQVHQ TTR (1-432 aa encoded by BC011901)
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39.1; CK-17; CK17; Cytokeratin-17; hard keratin; K17; keratin 17, type I; keratin complex 1, acidic, gene 17; Keratin, type I cytoskeletal 17; Keratin-17; krt17 {ECO:0000250|UniProtKB:Q04695}; Type I keratin Ka17
基因别名: 39.1; CK-17; K17; Ka17; Krt1-17; KRT17; PC; PC2; PCHC1
UniProt ID: (Human) Q04695, (Mouse) Q9QWL7, (Rat) Q6IFU8
Entrez Gene ID: (Human) 3872, (Mouse) 16667, (Rat) 287702