Progen

Cytokeratin 5/8 Monoclonal Antibody (C22)

Name: Cytokeratin 5\/8 Monoclonal Antibody (C22)
Brand: Progen
SKU: 65031
Price: ... USD
Availability: InStock

查看其他6个Cytokeratin 5/8抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (5)

Cytokeratin 5/8 Antibody in Immunohistochemistry (IHC)

图: 1 / 5

Cytokeratin 5/8 Antibody (65031) in IHC

Immunohistochemistry of mouse tongue (courtesy of J.H, University Hospital Heidelberg).

Cytokeratin 5/8 Antibody in Western Blot (WB)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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产品信息

65031

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化 (IHC)

Assay-dependent

免疫组化（石蜡） (IHC (P))

Ready-to-use

免疫组化（冰冻） (IHC (F))

Ready-to-use

产品规格

种属反应

Bovine, Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

C22

抗原

Human Keratin K8, Purified From Sds Page Gel

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

5 µg/mL

25 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 0.5% BSA

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Ambient (domestic); Wet ice (international)

产品详细信息

C 22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia. Polypeptide reacting: MW 52 500, MW 58 000 keratins (type II keratins K5 and K8; formerly also designated cytokeratins 5 and 8) of human epithelial cells.

靶标信息

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: 58 kDa cytokeratin; CK-5; CK-8; cytokeratin 5; cytokeratin 8; cytokeratin endo A; cytokeratin type II, component III; cytokeratin-5; cytokeratin-8; cytokeratin-A; EndoA cytokeratin (5' end put.); putative; EndoA' cytokeratin (5' end put.); putative; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; K8; KERA; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 8, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 8; keratin K5; keratin type II; keratin, type II cytoskeletal 60 kDa, component III; KRT5; tuftelin interacting protein 8; type II cytokeratin A (no.8); type-II keratin Kb5; type-II keratin Kb8; unnamed protein product

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基因别名: 3300001P10Rik; CARD2; CK-8; CK5; CK8; CYK8; DDD; DDD1; EBS1; EBS2; EBS2A; EBS2B; EBS2C; EBS2D; EBS2E; EBS2F; EndoA; K2C8; K5; K8; KO; Krt-2.8; Krt2-5; KRT2-8; KRT5A; Tfip8; TROMA-1