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Progen
Cytokeratin 8 Monoclonal Antibody (Ks8.7)
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产品信息
61038
应用
建议稀释比
已发表文章
产品规格
种属反应
Hamster,
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
Ks8.7
抗原
Cytoskeletal Proteins From Cultured Hela Cells
偶联物
形式
Lyophilized
浓度
0.05 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.5% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute lyophilized product with 1 mL distilled water.
Ks 8.7 represents an excellent marker to discriminate simple epithelia from those of different origin. Polypeptide reacting: MW 52 500 polypeptide (keratin K8; formerly also designated cytokeratin 8) of human epithelia.Reactivity on cultured cell lines: MCF-7Tumors specifically detected: All adenocarcinoma tested; undifferentiated carcinoma; cervix carcinoma; hepatocellular carcinoma.
靶标信息
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-8; Cytokeratin-8; K8; keratin 8; keratin 8, type II; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; Keratin-8; Type-II keratin Kb8
基因别名: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT8
UniProt ID: (Human) P05787
Entrez Gene ID: (Human) 3856, (Chinese hamster) 100759488
