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Invitrogen
DCAF12 Polyclonal Antibody
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产品信息
PA5-66479
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human TCC52
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: AGSDAQGPQFG WDHSLHKRKR LPPVKRSLVY YLKNREVRLQ NETSYSRVLH GYAAQQLPSL LKEREFHLGT L
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
靶标信息
Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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