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Proteintech
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Immunogen sequence: LGQPSLDSL PIPAPRGLVL VPSRELAQQV RAVAQPLGRS LGLLVRDLEG GHGMRRIRLQ LSRQPSADVL VATPGALWKA LKSRLISLEQ LSFLVLDEAD TLLDESFLEL VDYILEKSHI AEGPADLEDP FNPKAQLVLV GATFPEGVGQ LLNKVASPDA VTTITSSKLH CIMPHVKQTF LRLKGADKVA ELVHILKHRD RAERTGPSGT VLVFCNSSST VNWLGYILDD HKIQHLRLQG QMPALMRVGI FQSFQKSSRD ILLCTDIASR GLDSTGVELV VNYDFPPTLQ DYIHRAGRVG RVGSEVPGTV ISFVTHPWDV SLVQKIELAA RRRRSLPGLA SSVKEPLPQA T (191-540 aa encoded by BC024273)
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent RNA helicase Ddx28; DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 28; Mitochondrial DEAD box protein 28; mitochondrial DEAD-box polypeptide 28; Probable ATP-dependent RNA helicase DDX28
基因别名: 2410004K13Rik; AI449652; DDX28; MDDX28
UniProt ID: (Human) Q9NUL7, (Mouse) Q9CWT6
Entrez Gene ID: (Human) 55794, (Mouse) 71986, (Rat) 364995