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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PEPRPPQPSK TVPPHYPVVC CPTSGPQMCS KRPARGRATL GSQRKRRKSV TPDPKEKQTC DI
Antigen sequence identity: Mouse 97%; Rat 97%
DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDPro1; FLDED-1
基因别名: DEDD; DEDPRO1; DEFT; KE05
Entrez Gene ID: (Human) 9191