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May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cell cycle control protein SDP35; DEP domain-containing protein 1A
基因别名: DEP.8; DEPDC1; DEPDC1-V2; DEPDC1A; SDP35
UniProt ID: (Human) Q5TB30
Entrez Gene ID: (Human) 55635