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M5A is directed anti the C-terminal portion (part of the Catalytic domain) of rat DGKa.
The antibody may be stored at 4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 80 kDa diacylglycerol kinase; DAG kinase alpha; DGK-alpha; Diacylglycerol kinase alpha; diacylglycerol kinase, alpha 80kDa; Diglyceride kinase; Diglyceride kinase alpha; MGC12821; MGC42356
基因别名: DAGK; DAGK1; DGK-alpha; DGKA
UniProt ID: (Human) P23743
Entrez Gene ID: (Human) 1606