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Proteintech
DHFR Polyclonal Antibody
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产品信息
15194-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DHFR Fusion Protein Ag7331 (1-187 aa encoded by BC000192)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MVGSLNCIV AVSQNMGIGK NGDLPWPPLR NEFRYFQRMT TTSSVEGKQN LVIMGKKTWF SIPEKNRPLK GRINLVLSRE LKEPPQGAHF LSRSLDDALK LTEQPELANK VDMVWIVGGS SVYKEAMNHP GHLKLFVTRI MQDFESDTFF PEIDLEKYKL LPEYPGVLSD VQEEKGIKYK FEVYEKND (1-187 aa encoded by BC000192)
靶标信息
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, and is required for the synthesis of purines, thymidylic acid and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Dihydrofolate reductase; Dihydrofolate reductase 1 (active)
基因别名: 8430436I03Rik; AA607882; AI662710; AW555094; DHFR; Dhfr1; DHFRP1; DYR
UniProt ID: (Human) P00374, (Mouse) P00375, (Rat) Q920D2
Entrez Gene ID: (Human) 1719, (Mouse) 13361, (Rat) 24312
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
glycine biosynthetic process
tetrahydrobiopterin biosynthetic process
one-carbon metabolic process
nucleotide biosynthetic process
axon regeneration
response to methotrexate
dihydrofolate metabolic process
tetrahydrofolate metabolic process
tetrahydrofolate biosynthetic process
folic acid metabolic process
positive regulation of nitric-oxide synthase activity
oxidation-reduction process
regulation of removal of superoxide radicals
response to nicotine
