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Invitrogen
DIO2 Polyclonal Antibody
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DIO2 Antibody (PA5150219) in WB
Western blot analysis of DIO2 in Lane 1: Rat Heart lysate; Lane 2: Rat Skeletal muscle lysate. Samples were incubated with DIO2 Polyclonal (Product # PA5150219) antibody using a dilution of 0.5 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG (0.2 µg/mL).
产品信息
PA5150219
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant Deiodinase, Iodothyronine, Type II (DIO2) (Ser30-Phe259)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5DII; deiodinase, iodothyronine, type 2; DIOII; iodothyronine type II deiodinase; thyroxine deiodinase; thyroxine type II; Type 2 DI; Type II iodothyronine deiodinase; type-II 5' deiodinase; Type-II 5'-deiodinase
基因别名: 5DII; AI324267; Dio2; DIOII; Itdi2; Txdi2
UniProt ID: (Mouse) Q9Z1Y9, (Rat) P70551
Entrez Gene ID: (Mouse) 13371, (Rat) 65162
