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Proteintech
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Immunogen sequence: ELCDRDVRA CSSAPCANNG TCVSLDDGLY ECSCAPGYSG KDCQKKDGPC VINGSPCQHG GTCVDDEGRA SHASCLCPPG FSGNFCEIVA NSCTPNPCEN DGVCTDIGGD FRCRCPAGFI DKTCSRPVTN CASSPCQNGG TCLQHTQVSY ECLCKPEFTG LTCVKKRALS PQQVTRLPNG YGLAYRLTPG VHELPVQQPE HRILKVSMKE LNKKTPLLTE GQAICFTILG VLTSLVVLGT VGIVFLNKCE TWVSNLRYNH MLRKKKNLLL QYNSGEDLAV NIIFPEKIDM TTFSKEAGDE EI (83-383 aa encoded by BC007741)
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adenoma-associated variant of dlk1 protein; Adipocyte differentiation inhibitor protein; alternatively spliced; lacking 219 bp between positions 858 and 859; The 219 bp deletion has been demonstrated to originate by alternative splicing within an exon.; delta-like 1 homolog; dlk; DLK-1; EGF like function; fetal antigen 1; pG2; Preadipocyte factor 1; preadipocyte factor-1; PREF; Pref-1; Protein delta homolog 1; secredeltin; stromal cell derived protein 1; unnamed protein product
基因别名: AW742678; Delta1; DLK; DLK-1; DLK1; DlkI; FA1; Ly107; Peg9; pG2; Pref-1; PREF1; Scp-1; SCP1; ZOG
UniProt ID: (Human) P80370, (Mouse) Q09163, (Rat) O70534
Entrez Gene ID: (Human) 8788, (Mouse) 13386, (Rat) 114587