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Invitrogen
DLX5 Polyclonal Antibody
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DLX5 Antibody (PA5-101134) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded DLX5 in mouse heart tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with DLX5 polyclonal antibody (Product # PA5-101134) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101134
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DLX5(Accession P56178), corresponding to amino acid residues G106-F156.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DLX5.
靶标信息
This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DLX-3; Homeobox protein DLX-3; Homeobox protein DLX-5; RDLX
基因别名: AI385752; DLX5; RDLX
UniProt ID: (Rat) P50575, (Mouse) Q9JJ45
Entrez Gene ID: (Rat) 25431, (Mouse) 13395
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription regulatory region DNA binding
HMG box domain binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
osteoblast differentiation
endochondral ossification
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
axonogenesis
axon guidance
cell proliferation
embryonic limb morphogenesis
BMP signaling pathway
epithelial cell differentiation
inner ear morphogenesis
ear development
positive regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
positive regulation of epithelial cell proliferation
palate development
olfactory pit development
head development
face morphogenesis
bone morphogenesis
cellular response to BMP stimulus
positive regulation of canonical Wnt signaling pathway
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
ossification
multicellular organism development
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