Invitrogen

DMGDH Polyclonal Antibody

Name: DMGDH Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-57660

高级验证

查看其他6个DMGDH抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)
高级验证 (1)

DMGDH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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DMGDH Antibody (PA5-57660) in IHC (P)

Immunohistochemical analysis of DMGDH in human kidney using DMGDH Polyclonal Antibody (Product # PA5-57660) shows high expression.

DMGDH Antibody in Immunohistochemistry (IHC)

Product Image Gallery

DMGDH Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of DMGDH demonstrates antibody specificity. Immunohistochemical analysis of DMGDH using anti-DMGDH Polyclonal Antibody (Product # PA5-57660), shows significant staining of DMGDH in human kidney and shows minimal or weak staining in human colon tissues. The relative expression levels of DMGDH within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image DMGDH Polyclonal Antibody

产品信息

PA5-57660

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human DMGDH. Recombinant protein control fragment (Product #RP-96850).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2640628

产品详细信息

Immunogen sequence: TLATDDVDPE GNESIWYNGK VVGNTTSGSY SYSIQKSLAF AYVPVQLSEV GQQVEVELLG KNYPAVIIQE PLVLTEPTRN RLQK

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.

靶标信息

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。