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Invitrogen
DNA2 Polyclonal Antibody
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DNA2 Antibody (PA5-115131) in ICC/IF
Immunocytochemistry analysis of DNA2 in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115131). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115131
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DNA2(Accession P51530), corresponding to amino acid residues T430-G480.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DNA2L.
靶标信息
DNA2 is a conserved helicase/nuclease involved in themaintenance of mitochondrial and nuclear DNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA replication ATP-dependent helicase-like homolog; DNA replication helicase 2 homolog; DNA2 DNA replication helicase 2-like; DNA2-like helicase; KIAA0083; unnamed protein product
基因别名: DNA2L; E130315B21Rik; hDNA2; RTS4
UniProt ID: (Human) P51530, (Mouse) Q6ZQJ5
Entrez Gene ID: (Human) 1763, (Mouse) 327762
DNA replication checkpoint
telomere maintenance
DNA double-strand break processing
DNA replication
mitochondrial DNA replication
base-excision repair
telomere maintenance via semi-conservative replication
DNA geometric change
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
replication fork reversal
t-circle formation
mitotic telomere maintenance via semi-conservative replication
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