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Proteintech
DNAJA1 Polyclonal Antibody
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产品信息
11713-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DNAJA1 Fusion Protein Ag2284 (1-397 aa encoded by BC008182)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MVKETTYYD VLGVKPNATQ EELKKAYRKL ALKYHPDKNP NEGEKFKQIS QAYEVLSDAK KRELYDKGGE QAIKEGGAGG GFGSPMDIFD MFFGGGGRMQ RERRGKNVVH QLSVTLEDLY NGATRKLALQ KNVICDKCEG RGGKKGAVEC CPNCRGTGMQ IRIHQIGPGM VQQIQSVCME CQGHGERISP KDRCKSCNGR KIVREKKILE VHIDKGMKDG QKITFHGEGD QEPGLEPGDI IIVLDQKDHA VFTRRGEDLF MCMDIQLVEA LCGFQKPIST LDNRTIVITS HPGQIVKHGD IKCVLNEGMP IYRRPYEKGR LIIEFKVNFP ENGFLSPDKL SLLEKLLPER KEVEETDEMD QVELVDFDPN QERRRHYNGE AYEDDEHHPR GGVQCQTS (1-397 aa encoded by BC008182)
靶标信息
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1. 6 kb and a protein product with a molecular weight of about 35 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DnaJ (Hsp40) homolog, subfamily A, member 1; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; h HSJ-2; hDj-2; Heat shock 40 kDa protein 4; Heat shock protein J2; heat shock protein, DNAJ-like 2; HSDJ; HSJ-2; Human DnaJ protein 2; neural precursor cell expressed, developmentally down-regulated 7; neural precursor cell expressed, developmentally down-regulated gene 7
基因别名: DJ-2; DjA1; DNAJ2; DNAJA1; hDJ-2; HDJ2; HSDJ; HSJ-2; HSJ2; HSPF4; NEDD7
UniProt ID: (Human) Q86TL9, (Mouse) P63037
Entrez Gene ID: (Human) 3301, (Mouse) 15502
G-protein coupled receptor binding
protein binding
ATP binding
Hsp70 protein binding
Tat protein binding
ubiquitin protein ligase binding
metal ion binding
low-density lipoprotein particle receptor binding
unfolded protein binding
chaperone binding
C3HC4-type RING finger domain binding
heat shock protein binding
chaperone
protein folding
response to unfolded protein
spermatogenesis
response to heat
sperm motility
androgen receptor signaling pathway
negative regulation of protein ubiquitination
DNA damage response, detection of DNA damage
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of JUN kinase activity
regulation of protein transport
protein localization to mitochondrion
toxin transport
negative regulation of establishment of protein localization to mitochondrion
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
protein refolding
