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Proteintech
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Immunogen sequence: ILEPLLERRA SSGARVEDLS LREENSENRI SKFKRKDWSL SKSQVIAEKA PEPDLMSPTR KAQRPKSLQL MDNRLSPFHG SSPPQSTPLS PPPLTPKATR TLSSPSLQTD GIAATPVPPP PPPKSKPYEG SQRNSTELAP PLPVRREAKA PPPPPPKARK SGIPTSEPGS Q
Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dedicator of cytokinesis protein 5; dock5; FLJ21034; lens rupture 2; Lens rupture protein 2; Rupture of lens cataract protein
基因别名: 1110060D06Rik; AI666732; AI956923; BC016533; DOCK5; E130320D18; Lr2; Rlc
UniProt ID: (Human) Q9H7D0, (Mouse) B2RY04
Entrez Gene ID: (Human) 80005, (Mouse) 68813, (Rat) 305987