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Invitrogen
DOK4 Polyclonal Antibody
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DOK4 Antibody (PA5-14755) in IHC (P)
Immunohistochemistry analysis of DOK4 in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with DOK4 polyclonal antibody (Product # PA5-14755) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepato... View More
产品信息
PA5-14755
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 228-258 amino acids from the C-terminal region of human DOK4
偶联物
形式
Liquid
纯化类型
Size-exclusion - Dialysis, Ammonium sulfate precipitation
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse based on sequence homology.
靶标信息
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Docking protein 4; Downstream of tyrosine kinase 4; Insulin receptor substrate 5; IRS-5
基因别名: DOK4; IRS-5; IRS5
UniProt ID: (Human) Q8TEW6
Entrez Gene ID: (Human) 55715
