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Invitrogen
DOPA decarboxylase Recombinant Rabbit Monoclonal Antibody (19H9L9)
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图: 1 / 10
DOPA decarboxylase Antibody (704998) in ICC/IF
Immunofluorescence analysis of DOPA decarboxylase was performed using DOPA decarboxylase Recombinant Rabbit Monoclonal Antibody (19H9L9) (Product # 704998) on SH-SY5Y and SK-OV-3 cells. The cells were fixed with 4% paraformaldehyde for 10 min, permeabilized with 0.1% Triton™ X-100 for 15 min and blocked with 2% BSA for 1 hr at RT. The cells were labeled with DOPA decarboxylase Recombinant Rabbit Monoclonal ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
704998
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
19H9L9
抗原
Protein corresponding to human DOPA decarboxylase [aa1-aa480]
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2-7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Recombinant Rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
靶标信息
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); dopa decarboxylase (aromatic L-amino acid decarboxylase) isoform DDC_1; dopa decarboxylase (aromatic L-amino acid decarboxylase) isoform DDC_2; dopa decarboxylase (EC 4.1.1.28); HGNC:2719; L-Dopa decarboxylase; unnamed protein product
基因别名: AADC
UniProt ID: (Human) P20711, (Rat) P14173
Entrez Gene ID: (Human) 1644, (Rat) 24311
kidney development
cellular amino acid metabolic process
catecholamine metabolic process
circadian rhythm
response to toxic substance
gene expression
aminergic neurotransmitter loading into synaptic vesicle
dopamine biosynthetic process
dopamine metabolic process
catecholamine biosynthetic process
serotonin biosynthetic process
response to pyrethroid
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to xenobiotic stimulus
cellular biogenic amine biosynthetic process
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