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Invitrogen
DST Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76027
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human DST.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BPA; BPAG1a3; BPAG1eA; MACF-like product; BPAG1eB; second IF-binding domain product; bullous pemphigoid antigen; bullous pemphigoid antigen 1; cytoskeletal protein; cytoskeletal protein BPAG1; dystonia musculorum protein; hemidesmosomal plaque protein; microtubule actin cross-linking factor 2; trabeculin-beta; unnamed protein product
基因别名: 2310001O04Rik; A830042E19Rik; ah; athetoid; BP230; BP240; BPA; Bpag; BPAG1; BPAG1-n; CATX-15; CATX15; CMYO29; D6S1101; DMH; DT; EBS3; EBSB2; HSAN6; LCCS12; MACF2; mKIAA0728; nmf203; nmf339
UniProt ID: (Human) Q03001, (Mouse) Q91ZU6
Entrez Gene ID: (Human) 667, (Mouse) 13518, (Rat) 316313
microtubule cytoskeleton organization
cytoskeleton organization
axonogenesis
retrograde axonal transport
response to wounding
maintenance of cell polarity
regulation of microtubule polymerization or depolymerization
cytoplasmic microtubule organization
hemidesmosome assembly
wound healing
intermediate filament cytoskeleton organization
intracellular transport
cell motility
integrin-mediated signaling pathway
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