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Proteintech
DTX1 Polyclonal Antibody
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产品信息
18350-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DTX1 Fusion Protein Ag13172 (1-374 aa encoded by BC048216)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody recognizes DTX1 protein (72 kDa) and it's isoforms (about 60 kDa).
Immunogen sequence: MSRPGHGGL MPVNGLGFPP QNVARVVVWE WLNEHSRWRP YTATVCHHIE NVLKEDARGS VVLGQVDAQL VPYIIDLQSM HQFRQDTGTM RPVRRNFYDP SSAPGKGIVW EWENDGGAWT AYDMDICITI QNAYEKQHPW LDLSSLGFCY LIYFNSMSQM NRQTRRRRRL RRRLDLAYPL TVGSIPKSQS WPVGASSGQP CSCQQCLLVN STRAASNAIL ASQRRKAPPA PPLPPPPPPG GPPGALAVRP SATFTGAALW AAPAAGPAEP APPPGAPPRS PGAPGGARTP GQNNLNRPGP QRTTSVSARA SIPPGVPALP VKNLNGTGPV HPALAGMTGI LLCAAGLPVC LTRAPKPILH PPPVSKSDVK PVPGV (1-374 aa encoded by BC048216)
靶标信息
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: deltex 1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; Deltex1; E3 ubiquitin-protein ligase DTX1; fractionated x-irradiation induced transcript 1; FXI-T1; hDTX1; mDTX1; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
基因别名: DTX1; Fxit1; hDx-1; mKIAA4160
UniProt ID: (Human) Q86Y01, (Mouse) Q61010
Entrez Gene ID: (Human) 1840, (Rat) 687424, (Mouse) 14357
transcription coactivator activity
Notch binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
ubiquitin protein ligase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
transcription, DNA-templated
transcription from RNA polymerase II promoter
cell surface receptor signaling pathway
Notch signaling pathway
regulation of Notch signaling pathway
glial cell differentiation
protein ubiquitination
negative regulation of T cell differentiation
negative regulation of neuron differentiation
regulation of nucleic acid-templated transcription
