Progen

Desmocollin 3 Monoclonal Antibody (Dsc3-U114)

Name: Desmocollin 3 Monoclonal Antibody (Dsc3-U114)
Brand: Progen
SKU: 61093PROGEN

查看其他10个Desmocollin 3抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)

Desmocollin 3 Antibody in Immunohistochemistry (IHC)

图: 1 / 5

Desmocollin 3 Antibody (61093PROGEN) in IHC

Desmocollin 3 staining on human skin (courtesy of The Human Protein Atlas, www.proteinatlas.org, Thul PJ et al, 2017. A subcellular map of the human proteome. Science).

Desmocollin 3 Antibody in Western Blot (WB)

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Immunogen Image Desmocollin 3 Monoclonal Antibody (Dsc3-U114)

产品信息

61093PROGEN

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化 (IHC)

Assay-dependent

免疫组化（石蜡） (IHC (P))

1:10-1:100

免疫组化（冰冻） (IHC (F))

1:10-1:100

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

Dsc3-U114

抗原

Synthetic Peptide Corresponding To A Sequence Present On The Extracellular Anchor Domain Of Human Desmocollin 3 (Vhgapfyfsl pntspeisrl wsltkvc)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 0.5% BSA

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute lyophilized product with 1 mL distilled water.

Localizes Dsc3 present inall living epidermal layersin glandular duct cellsin basal matrix cells and outer root sheath of hair folliclesbasal and suprabasal cell layers of stratified epithelia (e.g. vagina, tongue, esophagus), basal layer of bladder urothelium and complex epithelium of tracheathymic reticulum cellsAll simple epithelia are negative. Intercalated disks of myocardium are negative. Polypeptide reacting: 109 kD and 100 kD polypeptides (desmocollin 3 splice isoforms at pI 5.2) from human epidermal desmosomes.Reactivity on cultured cell lines: Most cultured cell lines derived from stratified squamous epithelia or squamous cell carcinomas are positive (e.g. A-431, HaCaT).

靶标信息

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

仅用于科研。不用于诊断过程。未经明确授权不得转售。