Progen

Desmoglein 2 Monoclonal Antibody (10G11)

Name: Desmoglein 2 Monoclonal Antibody (10G11)
Brand: Progen
SKU: 61059

查看其他24个Desmoglein 2 (DSG2)抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

61059

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化（冰冻） (IHC (F))

1:10

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

10G11

抗原

Recombinant Peptide (220Aa Of 2Nd And 3Rd Extracellular Repeat Domain)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.05 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 0.5% BSA

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute lyophilized product with 1 mL distilled water.

Specificity: desmoglein 2 present in low concentrations in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells desmoglein 2 expression is generally very low. Polypeptide reacting: desmoglein 2 (1069aa; calculated mol. wt. 116,760)Reactivity on cultured cell lines: Many, including CaCo-2, HaCaT, MCF-7.

靶标信息

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

仅用于科研。不用于诊断过程。未经明确授权不得转售。