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Desmoglein 2 Monoclonal Antibody (G129)
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产品信息
651119S
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
G129
抗原
Recombinant Peptide (220Aa Of 2Nd And 3Rd Extracellular Repeat Domain)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Specificity: desmoglein 2 present in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells desmoglein 2 expression is generally very low. Polypeptide reacting: Desmoglein 2 (1069aa; calculated mol. wt. 116,760).Recommended as positive control: CaCo-2, HaCaT.Reactivity on cultured cell lines: Many, including CaCo-2, HaCaT, MCF-7.
靶标信息
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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