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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Dystrophin Antibodies

          NeoBiotechnologies

          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Monoclonal Antibody (DMD/3241)

          查看其他32个Dystrophin抗体

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          Cite Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Monoclonal Antibody (DMD/3241)

          • 抗体检测数据 (4)
          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 4

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          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody (1756-MSM1-P1ABX) in IHC (P)

          Formalin-fixed, paraffin-embedded human skeletal muscle stained with Dystrophin Monospecific Mouse Monoclonal Antibody (DMD/3241). {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody in Peptide array (ARRAY)
          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Antibody in SDS-PAGE (SDS-PAGE)
          Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) Monoclonal Antibody (DMD/3241)

          产品信息

          1756-MSM1-P1ABX

          应用
          建议稀释比
          已发表文章

          免疫组化(石蜡) (IHC (P))

          Assay-dependent
          -

          免疫组织化学(多聚甲醛固定) (IHC (PFA))

          1-2 µg/mL
          -

          酶联免疫吸附实验 (ELISA)

          Assay-dependent
          -

          肽阵列 (Array)

          Assay-dependent
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG1, kappa

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          DMD/3241

          抗原

          A recombinant fragment (around aa 114-263) of human DMD protein.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein A/G

          保存液

          PBS, pH 7.4

          内含物

          no preservative

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: Duchenne muscular dystrophy (DMD); Dystrophin; GS1-19O24.1; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592

          查看更多 收起

          基因别名: BMD; CMD3B; DMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85

          查看更多 收起

          UniProt ID: (Human) P11532

          查看更多 收起

          Entrez Gene ID: (Human) 1756

          查看更多 收起

          功能
          dystroglycan binding actin binding structural constituent of cytoskeleton protein binding zinc ion binding structural constituent of muscle myosin binding vinculin binding nitric-oxide synthase binding ubiquitin-protein ligase
          参与通路
          regulation of heart rate cytoskeleton organization muscle organ development regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion regulation of skeletal muscle contraction muscle attachment muscle filament sliding negative regulation of peptidyl-serine phosphorylation cellular protein localization response to muscle stretch peptide biosynthetic process cellular protein complex assembly muscle cell cellular homeostasis muscle fiber development cardiac muscle contraction regulation of ryanodine-sensitive calcium-release channel activity cardiac muscle cell action potential regulation of voltage-gated calcium channel activity negative regulation of peptidyl-cysteine S-nitrosylation positive regulation of sodium ion transmembrane transporter activity
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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