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Abnova
ECT2 Monoclonal Antibody (5D4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00001894-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
5D4
抗原
ECT2 (AAH06838.1, 46 a.a. approximately 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: LPKENWLKML CRHVANTICK ADAENLIYTA DPESFEVNTK DMDSTLSRAS RAIKKTSKKV TRAFSFSKTP KRALRRALMT SHGSVEGRSP SSNDKHVMSR
靶标信息
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epithelial cell-transforming sequence 2 oncogene; FLJ10461; guanine nucleotide exchange factor for Rho GTPases; MGC138291; Rho guanyl-nucleotide exchange factor; ECT2B; unnamed protein product
基因别名: ARHGEF31
UniProt ID: (Human) Q9H8V3
Entrez Gene ID: (Human) 1894
mitotic cytokinesis
nervous system development
activation of protein kinase activity
positive regulation of cytokinesis
intracellular signal transduction
positive regulation of protein import into nucleus
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of GTPase activity
positive regulation of neuron differentiation
regulation of protein kinase activity
regulation of small GTPase mediated signal transduction
protein homooligomerization
regulation of attachment of spindle microtubules to kinetochore
cellular response to hydrogen peroxide
bicellular tight junction assembly
cellular response to calcium ion
cellular response to ionizing radiation
activation of GTPase activity
positive regulation of mitotic cytokinetic process
regulation of cytokinesis, actomyosin contractile ring assembly
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