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Proteintech
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Immunogen sequence: MSEREVSTA PAGTDMPAAK KQKLSSDENS NPDLSGDEND DAVSIESGTN TERPDTPTNT PNAPGRKSWG KGKWKSKKCK YSFKCVNSLK EDHNQPLFGV QFNWHSKEGD PLVFATVGSN RVTLYECHSQ GEIRLLQSYV DADADENFYT CAWTYDSNTS HPLLAVAGSR GIIRIINPIT MQCIKHYVGH GNAINELKFH PRDPNLLLSV SKDHALRLWN IQTDTLVAIF GGVEGHRDEV LSADYDLLGE KIMSCGMDHS LKLWRINSKR MMNAIKESYD YNPNKTNRPF ISQKIHFPDF STRDIHRNYV DCVRWLGDLI LSKSGRAILH SHQQCMRDPV SPNLRQHLSC ENAIVCWKPG KMEDDIDKIK PSESNVTILG RFDYSQCDIW YMRFSMDFWQ KMLALGNQVG KLYVWDLEVE DPHKAKCTTL THHKCGAAIR QTSFSRDSSI LIAVCDDASI WRWDRLR (1-466 aa encoded by BC068995)
The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin Beta-7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Embryonic ectoderm development protein; hEED; Polycomb protein EED; WAIT-1; WD protein associating with integrin cytoplasmic tails 1
基因别名: EED; HEED; WAIT1
UniProt ID: (Human) O75530
Entrez Gene ID: (Human) 8726