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Invitrogen
EFHA1 Polyclonal Antibody
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产品信息
PA5-66208
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human EFHA1
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: MLDTDGNEMIE KREFFKLQKI ISKQDDLMTV KTNETGYQEA IVKEPEINTT LQMRFFGKRG QRKLHYKEFR RFMENLQTEI QEMEFL
Highest antigen sequence identity to the following orthologs - mouse 80%, rat 79%.
靶标信息
Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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