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Abnova
EFHC2 Polyclonal Antibody, MaxPab™
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产品信息
H00080258-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EFHC2 (NP_079460, 1 a.a. approximately 749 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MALPLLPGNS FNRNVGKEKF HKSQHWGFCN NVMMLVSDEK PGIGGEPLLG QKIKPKCSIY PKGDGSDVPS WVAFDKQVLS FDAYLEEEVL DKSQTNYRIR YYKIYFYPED DTIQVNEPEV KNSGLLQGTS IRRHRITLPP PDEDQFYTVY HFNVGTEVVF YGRTFKIYDC DAFTRNFLRK IGVKVNPPVQ CPEDPYMKIR REVVEHVEPL RPYESLDTLK QFLQYHGKIL CFFCLWDDSV SMFGDRRELI LHYFLCDDTI EIKELLPHSS GRDALKMFLR RSKLPKNCPP RVYQPGQITD RAVLNSYGDF IKNQADGYLF DRYKLGKVDQ EFYKDSDLSL GVTINVWGRK VLLYDCDEFT KSYYKSKYGI ENFTSVSCKP PSPPPKIERK FPPYNGFGSE EDSLRNCIDL KPTPHRRNFK KFMEKDSYGS KSNILRFFAK LVTDKCVDLD RMFVISYYLG DDTISVFEPI ERNSGIAGGM FLKRSRVKKP GQEVFKSELS EYIKAEELYI GVTVNVNGYL FRLLNADEYT LNYMEQNTDK YPFSNLKLAL QKLKQEEGKS RELKQVFKAA DSKHTNMVDY NTFRDILMSL TVGNLAEQEF VTIARHYRVP EGTCSDMDFL IALAHEKFKK NMFENFDTFI YSCVYEDREK KNVLPTKDIK RLCKSSRLPL SDDLLESLLS RFEDSEKQID YKSFFSALNW RKNPVPELQP ASYLKERCED VWLGMPSPIP AKYIDYWTFL KDAFGLEEE
靶标信息
EFHC2 (EF-hand domain-containing protein 2) is a gene located on the X chromosome at position Xp11.4. The protein encoded by EFHC2 is characterized by the presence of EF-hand motifs, which are helix-loop-helix structural domains capable of binding calcium ions. The EFHC2 protein is involved in various cellular processes, particularly those that are calcium-dependent, such as signal transduction and regulation of enzyme activities. EFHC2 has been implicated in neurological functions and conditions. For instance, it has been studied in the context of epilepsy, where variants in the gene are associated with increased susceptibility to juvenile myoclonic epilepsy. Additionally, EFHC2 is expressed in the brain and testis, suggesting roles in neurodevelopment and reproduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EF-hand domain (C-terminal) containing 2; EF-hand domain-containing family member C2; mental retardation, X-linked 74
基因别名: dJ1158H2.1; EFHC2; MRX74
UniProt ID: (Human) Q5JST6
Entrez Gene ID: (Human) 80258
