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Invitrogen
EGR4 Polyclonal Antibody
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EGR4 Antibody (PA5-116975) in WB
Western blot analysis of EGR4 in mouse brain. Samples were incubated with EGR4 Polyclonal antibody (Product # PA5-116975) followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
产品信息
PA5-116975
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_0019563)
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse brain
Immunogen sequence: GVAAPPVPPP PPTPFPQAKA RRKGRRGGKC STRCFCPRPH AKAFACPVES CVRSFARSDE LNRHLRIHTG HKPFQCRICL RNFSRSDHLT THVRTHTGEK PFACDVCGRR FARSDEKKRH SKVHLKQKAR AEERLKGLGF YSLGLSFASL
靶标信息
Early growth response protein 4 (EGR-4), also known as AT133, is a protein that in humans is encoded by the EGR4 gene. EGR-4 is a member of the early growth response (EGF) family of zinc finger transcription factors. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AT133; Early growth response protein 4; Early response protein NGFI-C; EGR-4; Nerve growth factor-induced protein C; NGFI-C; zinc-finger transcription factor NGFI-C (early response gene)
基因别名: Egr-4; EGR4; Egr4l1; NGF1-C; NGFI-C; NGFIC; PAT133
UniProt ID: (Human) Q05215, (Rat) Q00911, (Mouse) Q9WUF2
Entrez Gene ID: (Human) 1961, (Rat) 25129, (Mouse) 13656
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
cellular response to cAMP
cellular response to growth factor stimulus
cellular response to gonadotropin stimulus
