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PA1-31612 detects ESE1 from human samples.
PA1-31612 has been successfully used in Western blot applications. A suggested positive control for this product is NCI-H460 lysate.
The PA1-31612 immunogen is peptide with sequence SGWKEEEVLQSRN, from C Terminus of the protein sequence according to NP_004424
ESE-1 (Epithelium-Specific Ets) is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family, which has features distinct from those of any other ets-related factor. ESE-1 binds with high affinity to and transactivates the ets binding site in the promoter of the keratinocyte terminal differentiation marker gene, SPRR2A. ESE-1 is a critical regulator of epithelial cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。