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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: CFFRQSTDPF ATSSTDPFSA ANNSSITSVE TLKHNDPFAP GGTVVAASDS ATDPFASVFG NESFGGGFAD FSTLSKVNNE DPFRSATSSS VSNVVITKNV FEETSVKSED EPPALPPKIG TPTRPCPLPP GKRSINKLDS PD
Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 83%.
EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: accessory endocytosis protein; AF-1p; AF-1p protein; ALL1 fused gene from chromosome 1; protein AF-1p; unnamed protein product
基因别名: AF-1P; AF1P; MLLT5
UniProt ID: (Human) P42566
Entrez Gene ID: (Human) 2060