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Invitrogen
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Immunogen sequence: DLVVVLVDVS DKWTRNQLSP QLLRCLTKYS QIPSVLVMNK VDCLKQKSVL LELTAALTEG VVNGKKLKMR QAFHSHPGTH CPSPAVKDPN TQSVGNPQRI GWPHFKEIFM LSALSQEDVK TLKQYLLTQA QPGPWEYHSA VLTSQTPEEI CANIIREKLL EHLPQEVPYN VQQKTAVWEE GPGGELVIQQ KLLVPKESYV KLLIGPKGHV ISQIAQEAGH DLMDIFLCDV DIRLSVKLLK; Positive Samples: SKOV3, HeLa, U-87MG, NCI-H460, Mouse kidney, Mouse heart, Rat liver; Cellular Location: Mitochondrion inner membrane, Mitochondrion matrix, Peripheral membrane protein
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CEGA; Conserved ERA-like GTPase; era (E. coli G-protein homolog)-like 1; Era G-protein-like 1; Era-like 12S mitochondrial rRNA chaperone 1; ERA-like protein 1; ERA-W; GTP-binding protein era homolog; GTPase Era, mitochondrial; GTPase, human homolog of E. coli essential cell cycle protein Era; H-ERA
基因别名: CEGA; ERA; ERA-W; ERAL1; ERAL1A; H-ERA; HERA; HERA-A; HERA-B
UniProt ID: (Human) O75616
Entrez Gene ID: (Human) 26284