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Invitrogen
ERAS Polyclonal Antibody
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ERAS Antibody (PA5-71907) in ICC/IF
Immunofluorescence analysis of ERAS Antibody (N-term) in HeLa cells. Samples were incubated with ERAS polyclonal antibody (Product # PA5-71907) with a dilution of 0.025 mg/mL. Alexa Fluor 546-conjugated donkey anti-rabbit lgG (H+L) was used as a secondary antibody. Nuclei were stained with DAPI (blue).
产品信息
PA5-71907
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human ERAS
偶联物
形式
Liquid
浓度
3.84 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
靶标信息
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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