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Proteintech
ERLIN1 Polyclonal Antibody
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产品信息
17311-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ERLIN1 Fusion Protein Ag11279 (29-346 aa encoded by BC031791)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: GHLAVYYRG GALLTSPSGP GYHIMLPFIT TFRSVQTTLQ TDEVKNVPCG TSGGVMIYID RIEVVNMLAP YAVFDIVRNY TADYDKTLIF NKIHHELNQF CSAHTLQEVY IELFDQIDEN LKQALQKDLN LMAPGLTIQA VRVTKPKIPE AIRRNFELME AEKTKLLIAA QKQKVVEKEA ETERKKAVIE AEKIAQVAKI RFQQKVMEKE TEKRISEIED AAFLAREKAK ADAEYYAAHK YATSNKHKLT PEYLELKKYQ AIASNSKIYF GSNIPNMFVD SSCALKYSDI RTGRESSLPS KEALEPSGEN VIQNKESTG (29-346 aa encoded by BC031791)
靶标信息
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; Endoplasmic reticulum lipid raft-associated protein 1; Erlin-1; OTTHUMP00000059425; OTTHUMP00000197867; Protein KE04; Protein KE04 homolog; SPFH domain family, member 1; SPFH domain-containing protein 1; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
基因别名: 2810439N09Rik; C10orf69; C80197; Erlin-1; ERLIN1; KE04; KEO4; RGD1307058; SPFH1; SPG62
UniProt ID: (Human) O75477, (Mouse) Q91X78
Entrez Gene ID: (Human) 10613, (Rat) 293939, (Mouse) 226144
